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Past Projects

Former Funded Projects of the MBRS-SCORE Program.

Cycle 9 :
Project Name
Years
PI's
The Unique Hemoglobin I of L. pectinata : A Study of the Heme (FeIV=O) Moiety.
2004 a 2007
Dr. Juan López Garriga 
Squeeze-out and re-uptake of Pulmonary Surfactant Components.
2004 a 2007
Dr. Gustavo Lopez and Dr. Belinda Pastrana-Rios 
Design of Ti(IV) and Mo(IV) Complexes with Antitumor Properties: Synthesis and biochemical Characterization.
2004 a 2007
Dr. Enrique Melendez 
MAP Kinase Pathways in the Yeast Debaryomyces hansenii.
2004 a 2007
Dr. Govind S. Nadathur 
Conformational Changes in Phosphorylated Proteins.
2004 a 2007
Dr. Belinda Pastrana-Rios
Examination of the mechanisms of Interaction of PEG-rich Matrices with the MRP and MDR Transporters.
2004 a 2007
Dr. Madeline Torres-Lugo
Cycle 8 :
Project Name
Years
PI's
Role of stress in expression of mammalian secondary hormones (eicosanoids) in red algae
2000-2003
Dr. David Ballantine, Dra. Nilda Aponte 
Identification of Regulatory Elements in the sequence of Parvovirus LullI 
1999-2003
Dra. Nannette Diffoot 
An unique H2S- Hemoglobin I structure : a site- directed mutagenesis study
1999-2003
Dr. Juan López Garriga
Synthesis, Kinetics, DNA-Metal Interaction and Biological Activity of Titanocene Derivates 
1999-2003
Dr. Enrique Melendez 
A Universal Crystallographic FFT Package 
1999-2003
Dr. Jaime Seguel, Dra Dorothy Bollman
Changes in Conformation of Phosphorylated Proteins
1999-2003
Dr. Belinda Pastrana-Rios 
Branched or cross linked poly (anhydride-co-imides) for Peptide/Protein Release 
2000-2003
Dr. Carlos Ramirez, Dra. Maria Aponte 
Cycle 7 :
Project Name
Years
PI's
Role and Production of Biologically Active Secondary Metabolites from Marine Algae
1996-1999
Dr. David Ballantine, Dra. Nilda Aponte 
Studies of a Putative Encapsidation signal(s) in Parvovirus Lulll
1995-1999
Dr. Nannette Diffoot
Proximate Control of Reproduction Success in Ameiva Exsul 
1995-1999
Dr. Allen R. Lewis 
Molecular population, Genetics, and Evolution of Hawaiian Drosophila 
1995-1999
Dr. Juan C. Martinez  
Interaction and Biological Activity of Titanocene Derivate
1997-1999
Dr. Enrique Meléndez 
Characterization of Enviromentally Induced Genes in the Yeast Debaryomyces hansenii
1995-1999
Dr. Govind Nadathur 
Amino Acid –Containing Polyanhydrides for peptide and Protein Release (Protein Release)
1995-1999
Dr. Carlos Ramirez, Dra. Maria Aponte 
Synthesis of Symmetrical Bis-Partial Intercalators and study of their Effects on Nucleic Acids Conformation
1995-1999
Dr. Marisol Vera,Dr. Cynthia Robledo 
Cycle 6 :
Project Name
Years
PI's
Production & regulation of Production of Antibiotic &Eicosanoid Metabolites by Red Algae 
1991-1995
Dr. David Ballantine, Dr. William Gerwick
Characterization & Inhibition studies of the toxin (s) produced by R. Phaseoli 
1991-1995
Dr. Emilio Díaz,  Dra. Doris Ramirez
Social Control of male reproductive success in a non-territorial lizard 
1991-1995
Dr. Allen R. Lewis 
Heme Proteins Ligand Dynamics:  The C=O Poison Thereshold  
1991-1995
Dr. Juan López Garriga 
Molecular Evolutionary Genetics of Hawaiian Drosophila Chorion 
1991-1995
Dr. Juan Martínez Cruzado
Sperm availability and environmental influences on sex differentiation
1991-1995
Dr. Douglas Shapiro 
Seafood Poisons: Detection of Ciguatoxic Fish
1991-1995
Dr. Thomas Tosteson 
NMR Studies of Oligopeptide- Nucleic Acid Complexes
1991-1995
Dr. Marisol Vera, Dr. Cyntia Robledo
Cycle 5 :
Project Name
Years
PI's
Regulation of secondary metabolite production in bioactive algae 
1988-1991
Dr. David Ballantine, Dr. William Gerwick 
Endothelial intracellular membrane bound and secreted sulfates proteoglycans 
1988-1991
Dr. Carlos Castillo 
Interactions of Tetrapeptide containing Aromatic Residues with Nucleic Acids 
1988-1991
Dr. Cynthia Robledo, Dr. Marisol Vera
Reproductive Electrophysiology of Rhesus Monkey 
1988-1991
Dr. Eric Phoebus, Dr. Robert Smith, Dr. Matt Kessler 
Hybrid Artificial pancreas for glucose regulation 
1988-1991
Dr. Carlos Ramírez, Dr. Carlos Fierro 
Physiology and Behavior of adult sex change in Fish 
1988-1991
Dr. Douglas Y. Shapiro 
Ciguatera Toxins: Seasonality and Detection
1988-1991
Dr. Thomas Tosteson, Dr. David Ballentine
Cycle 4 :
Project Name
Years
PI's
Interactions of Oligopeptides with Nucleic Acids  
1985-1988
Dr. Cynthia M. Robledo 
Hybrid Artificial pancreas for glucose regulation 
1985-1988
Dr. Carlos Ramírez, Dr. Carlos Fierro 
Mechanism for photoreceptor cell organelle movement 
1985-1988
Dr. George Miskimen, Dr. Michael J. Wilcox 
Physiology and Behavior of adult sex change in Fish 
1985-1988
Dr. Douglas Y. Shapiro 
Reproductive Electrophysiology of Rhesus Monkey 
1985-1988
Dr. Eric Phoebus, Dr. Robert Smith, Dr. Matt Kessler 
Cycle 2 :
Project Name
Years
PI's
Electrophysiology, Morphology and Ultrastructure  of Insects Sensory Structures 
1979-1982
Dr. George Miskimen, Dr. Jaime Roman, Dr. Hardeo Sahai, Dr. Herndon Agge
Biochemical Raman Spectroscopy 
1979-1982
Dr. Tze Chi Jao, Dr. Jaime Roman
Exogenous DNA Incorporation in Plant Protoplasts 
1979-1981
Dr. Francis Koo 
Development of Analytical of Electrophoretic technique for the characterization of serum proteins
1979-1981
Dr. Carlos  Castillo 
Pharmacological activity of Marine Microbial  Exudates 
1979-1981
Dr. Thomas Tosteson, Dr. Tai Robert S-C. 
Cycle 3 :
Project Name
Years
PI's
Electrophysiology and Functional Morphology of Visual Sensory Structures 
1982-1985
Dr. George Miskimen, Dr. Jaime Roman, Dr. Hardeo Sahai, Dr. Herndon Agge
Behavioral control of sex change in Fish Social Groups 
1982-1985
Dr. Douglas Y. Shapiro 
Cycle 1 :
Project Name
Years
PI's
Electrophysiology  of Insects Sensory Structures 
1974-1979
Dr. George Miskimen, Dr. Carmen R. Miskimen, Dr. Jaime Arbona Fazzi 
Pathophysiology of Tissue cultured Invertebrate Cells 
1974-1976
Dr. Goro Kuno, Dr. Flavio Padovani 
Spectroscopic Studies of Carcinogenic Molecules 
1974-1976
Dr. MEM Abu- Zeid, Dr. Federico Herrero
Biochemical Raman Spectroscopy 
1976-1979
Dr. Tze Chi Jao, Dr. Jaime Roman
Development of a Predictive Population Model for the Yellow fever mosquito Aedes aegypty
1974-1975
Dr. C.G. Moore, Dr, W.A Heenan, Dr. Mario Padron, Dr. Flavio Padovani.
Electron Micoscopy of Invertebrate Neuromuscular  System
1977-1979
 Dr. George Miskimen, Dr. José del Castillo



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MBRS-SCORE Program
University of Puerto Rico at Mayagüez
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Main Building, Office 210
Mayaguez, PR